Genome Tape vs Cloud Cold Storage

A simplified model for ~200 whole genomes per year: cold archive on LTO tape, with local HDD/SSD working storage, compared to cloud cold/archive storage with and without re-read/reanalysis costs.

Workload

Cloud cold storage rates

Separate cloud rows show: pure offsite cold backup with zero reads, and cloud cold storage where the archive is read back for reanalysis.


Tape cold storage: base package

Local working storage

Defaults: Quantum SuperLoader 3 style package: 8 slots, LTO-8, 96 TB native full, quoted at $10k for the unit. LTO-8 tapes default to $100 each and 12 TB native.

Final archive
Tapes needed
Robot full capacity
Break-even size

Tape vs cloud cold storage

Cloud backup, no readsCloud with reads/reanalysisTape + local storage upfrontBreak-even

Selected local storage capacities

Storage areaRaw / purchasedUsableCostNotes

Cost summary

OptionUpfrontRecurring/read costTotal over yearsEffective $/TB-yearEffective $/genome-year

Tape and local hardware details

ItemQuantityCapacityUnit costTotalNotes

Year-by-year cloud vs tape

YearGenomesArchive sizeCloud no-read cumulativeCloud with reads cumulativeTape/local cumulative

Reference links

Cloud pricing: AWS S3, Azure Blob, Google Cloud Storage. Tape references: LTO Program, Quantum SuperLoader 3.